President William McKinley's portrait appeared on which large U.S. bill, last printed in 1945?

On a prescription, the abbreviation "b.i.d." tells you to take a medicine how many times a day? In "The Devil's Dictionary," Ambrose Bierce defined which event as "the first and direst of all disasters"? Which word completes both insults "thick as a ___" and "one ___ short of a load"? London and Sault Ste. Marie are cities in which Canadian province? Which brand's Whitestrips tooth-whitening product first hit store shelves nationally in 2001? Which building appears on the back of the U.S. $5 bill? Raymond Chandler's private eye Philip Marlowe works in which big city? Mark Twain was born in 1835, the year which famous comet appeared?