In which 1980 comedy does a doctor say "I am serious... and don't call me Shirley"?

The 1980 failure of "Heaven's Gate" led Transamerica to sell which film studio to MGM? In which 1980 film do two shipwrecked children grow up on a tropical island to be Brooke Shields and Christopher Atkins? Who won the Best Actor Oscar for playing Jake LaMotta in "Raging Bull"? In which 1980 film does a madman smash through a door and announce "Heeere's Johnny!"? In which 1980 comedy does Lloyd Bridges say "Looks like I picked the wrong week to quit sniffing glue"? Which 1980 TV miniseries featured extensive Japanese dialogue and starred Richard Chamberlain as an English navigator? Paul Berg shared the 1980 Nobel Prize in Chemistry for pioneering which technique of splicing genetic material from dif… Proverbially, you can have one on your back or make one out of someone. What is it?