At about 43,000 square miles, which is the largest independent island nation in the Western Hemisphere?

Orbiting at about 17,500 mph, which winged NASA spacecraft flew 135 missions between 1981 and 2011? Which is the longest African river that empties into the Indian Ocean? At about 25,000 feet down, the Cayman Trench is the deepest part of which sea? Which Nepalese peak, at about 29,000 feet, is the highest mountain on Earth above sea level? Red Lake, at about 440 square miles, is the largest natural lake entirely within which "Land of 10,000 Lakes" state? At about 63,000 feet, the low air pressure would cause blood at normal body temperature to do what? Which very large brown bear shares its name with an Alaskan island? At over 7,000 feet, which Western Hemisphere city is the highest ever to host the Summer Olympics?